Inreasing Efficacy and Decreasing foxicity of Chinese Medicine Combined with Oxaliplatin in the Treatment of Cancer
- VernacularTitle:中药联合奥沙利铂治疗癌症的增效减毒作用概述
- Author:
Yuanfeng ZHANG
;
Tuo SHI
;
Ming XIE
;
Chenglong LI
- Keywords:
Oxaliplatin;
Chinese medicine;
Combinahon;
Increasing efficacy;
Decreasing foxicity
- From:
China Pharmacist
2017;20(7):1218-1223
- CountryChina
- Language:Chinese
-
Abstract:
Oxaliplatin, a third-generation platinum-based compound with significant activity against tumors, has become pivotal for the therapy of cancer after cisplatin and carboplatin.The digestive tract reaction, myelosuppression and nephrotoxicity have been alleviated, however, oxaliplatin induced neurotoxicity occurs prominently.Therefore, how to effectively eliminate and prevent chemotherapy-induced side and toxic effects becomes a great challenge for oncologists.plenty of evidence has hinted that combination of Chinese herbal medicine and oxaliplatin can not only reduce the toxicity, but also improve the actual efficacy, clinical research and experimental researches on increasing off cacy and decresing foxcity of Chinese herbal medicine combined with oxali-platin in the treatment of cancer in recent years were rewewed.to provide reference for the clinical use of oxaliplatin-based chemotherapy regimen.
