A new challenge to the diagnosis and treatment of sepsis: Persistent inflammation immuno-suppression catabolism syndrome

VernacularTitle:脓毒症诊疗的新挑战——持续炎症、免疫抑制和分解代谢综合征
Author: Weiqin LI
Keywords: Sepsis; Persistent inflammation immuno-suppression catabolism syndrome; Chronic critical illness; Immunotherapy
From: Journal of Medical Postgraduates 2017;30(7):673-677
CountryChina
Language:Chinese
Abstract: The early mortality of sepsis patients has been largely decreased since the publication of the Surviving Sepsis Campaign guidelines.However, the poor long-term prognosis, high 3-year mortality, impaired mental and physical functions, and tremendous financial burden constitute a new challenge to the treatment of sepsis.Persistent inflammation immuno-suppression catabolism syndrome (PICS) is known to be a definite factor affecting the long-term prognosis of sepsis.This article presents a systematic review of the concept, pathogenesis and treatment strategies of PICS, hoping to provide a new approach to the diagnosis and management of sepsis.