Research Progress in Nano Preparations of Artemisinin and its Derivatives in Anti-tumor Fields
- VernacularTitle:青蒿素及其衍生物纳米制剂在抗肿瘤领域中的研究进展
- Author:
Yang GUAN
;
Linyan WANG
;
Bingqian HE
;
Songwei TAN
- Keywords:
Artemisinin;
Artemisinin derivatives;
Nano drug delivery system;
Anti-tumor;
Transferrin
- From:
China Pharmacist
2017;20(7):1275-1278
- CountryChina
- Language:Chinese
-
Abstract:
Artemisinin and its derivatives have shown the potential application value in anti-tumor fields.But their applications are limited due to poor solubility, short half-life and so on;therefore, many scholars devoted themselves to developing and studying relative pharmaceutical preparations.Nano drug delivery system is a new drug delivery tool.Compared with the traditional dosage forms, such as tablets, suppositories and injections, nano drug delivery system has such advantages as good stability, targeted drug release and combined drug delivery.In this review, nano drug delivery carriers for artemisinin were summarized, including nanoparticles, liposomes, micelles, nanomicroemulsions and so on.The research results and characteristics of artemisinin-containing nano formulas in tumor therapy, as well as the co-delivery system of artemisinin and transferrin, were discussed.
