NOD proteins and immune response
10.3969/j.issn.1000-484X.2017.06.001
- VernacularTitle:NOD蛋白与免疫应答
- Author:
Xueying SHEN
;
Chuanlei FANG
;
Zhihua LIU
- Keywords:
NOD protein;
Cellular localization;
Physiological function
- From:
Chinese Journal of Immunology
2017;33(6):801-810
- CountryChina
- Language:Chinese
-
Abstract:
The NOD protein family include NOD1 and NOD2,both of which recognize intracellular bacterial peptidoglycan,induce inflammation and promote host defense.In this review article,we summarize the research progress on NOD family,including signaling and regulation.We will also discuss their cellular localization and the role in host defense.Understanding on their physiological function will help shed light on pathogenesis on related diseases.
