Thrombolytic therapy for treatment of Moyamoya disease and acute cerebral infarction: a successful case report
10.3969/j.issn.1008-9691.2017.04.025
- VernacularTitle:烟雾病并发急性脑梗死溶栓治疗成功案例举隅
- Author:
Feng GAO
;
Xiaona WEI
;
Tingyi SONG
- Keywords:
Moyamoya disease;
Acute cerebral infarction;
Reteplase;
Thrombolytic therapy
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2017;24(4):435-436
- CountryChina
- Language:Chinese
-
Abstract:
Moyamoya disease is a chronic progressive cerebrovascular disease. It got its nickname, the moyamoya disease, because the image of abnormal blood vascular net at the skull base in the encephaloangiography of such patients is very similar to smog. The moyamoya disease can be divided into two types: ischemic and hemorrhagic according to its clinical manifestations and imaging characteristics. In the ischemic type of moyamoya disease, when the blood vascular lumens are not narrow enough to completely block the blood flow, the chief manifestation is the cerebral blood circulation insufficiency; when the salvage is not in time, the disease will further progress to develop vascular obstruction or thrombosis, resulting in cerebral infarction, finally hemiplegia, aphasia, etc. irreversible symptoms and signs occur. In the primary hospital, the first choice for treatment of acute cerebral infarction (ACI) is drug thrombolysis. However, the main treatment for moyamoya disease with ACI is chiefly revascularization. This article reported a patient with moyamoya disease and ACI successfully treated by intravenous reteplase for thrombolysis in People's Hospital of Pucheng County.
