Acupuncture for dry eye syndrome: a meta-analysis of randomized controlled trials
10.1007/s11726-017-1011-1
- VernacularTitle:针刺治疗干眼症的Meta分析
- Author:
Huiru JIANG
;
Sujun LIU
;
Peng LIU
;
Siwei XU
;
Yang YANG
;
Kaiyong ZHANG
;
Yin SHOU
;
Bimeng ZHANG
- Keywords:
Acupuncture Therapy;
Dry Eye Syndrome;
Randomized Controlled Trial;
Systematic Review;
Meta-analysis
- From:
Journal of Acupuncture and Tuina Science
2017;15(4):263-269
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To summarize and critically assess the evidence from randomized controlled trials (RCTs) of acupuncture in treating dry eye syndrome (DES) according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and the Cochrane Collaboration recommendations. Methods: A search of PubMed, the Cochrane Central Register of Controlled Trials, ClinicalTrials.gov and Embase was made from their inception to August 2016, as well as Chinese, Japanese, and Korean databases. Two reviewers independently selected RCTs and assessed the methodological quality. Meta-analysis and the level of evidence were processed by RevMan 5.3 and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Results: After selection, 8 trials were subjected to our systematic review. The methodological quality was low generally. The 3-10 weeks follow-up showed that acupuncture improved the tear film break-up time (BUT) (MD=1.33, 95%CI=1.01-1.66, 619 participants). The mean difference of Schirmer's test was 1.73 mm (95%CI=1.28-2.18, 618 participants) between the acupuncture group and the control group. The subjective variables exhibited no significant differences. Conclusion: The low methodological quality of the trials does not suggest drawing firm conclusions on the value of acupuncture therapy for DES. Acupuncture treatment may have some effects on the tear film BUT and Schirmer's test, but not on the subjective symptoms. Well-planned large-scale high-quality RCTs are needed to make it clear whether acupuncture is effective in treating DES.
