Influence of renal damage on acute exacerbation of chronic obstructive pulmonary disease and hospitalizations
10.3969/j.issn.1671-8348.2017.21.016
- VernacularTitle:肾损伤对慢性阻塞性肺疾病急性加重及住院的影响
- Author:
Shihong LI
;
Liming ZHANG
;
Baosen PANG
;
Junling LIN
;
Yingmin MA
- Keywords:
pulmonary disease;
chronic obstructive;
kidney injury;
acute exacerbation;
hospitalization;
prognosis
- From:
Chongqing Medicine
2017;46(21):2934-2936
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of chronic renal disease (CKD) on acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and hospitalization.Methods Fifty patients clinically diagnosed as COPD complicating CKD in our hospital from January 2011 to June 2013 were selected as the observation group and 50 patients with CKD-free COPD were taken as a control group.The comparative analysis was performed by retrospecting the data of lung function,exercise tolerance and hospitalization situation in 1 year follow up.Results The mortality rate,total occurrence rate of AECOPD,occurrence rate of severe AECOPD,hospitalization rate,hospitalization time,self-rating test (CAT) score,mMRC dyspnea index,CRP and blood creatinine level in the observation group were higher than those in the control group,the difference was statistically significant (P<0.05);FEV1%pred,6MWD and creatinine clearance rate in the observation group were lower than those in the control group,the difference was statistically significant (P<0.05);FEV1/FVC had no statistical difference between the two groups (P>0.05).Conclusion The condition in COPD patients complicating CKD at 1 year after clinical diagnosis is significantly aggravated compared with COPD patients without complicating CKD,and the prognosis for patients complicated with CKD is poorer.
