Recent advance in surgical treatment of pancreatic neuroendocrine tumors

VernacularTitle:胰腺神经内分泌肿瘤外科治疗的最新研究进展
Author: Min YANG ; Chunlu TAN ; Nengwen KE ; Xubao LIU
Keywords: Pancreatic neuroendocrine tumors; Grading; Surgery; Hepatic metastasis
From: Chinese Journal of Endocrine Surgery 2017;11(3):241-244
CountryChina
Language:Chinese
Abstract: Pancreatic neuroendocrine tumors (P-NETs) are a group of heterogeneous tumors,including functional and nonfunctional ones.With the enhancement of clinicians' awareness about this disease and the improvement of imaging diagnostic techniques,the incidence of P-NETs has obviously increased in the past years.Based on the mitotic counting and Ki-67 positive index,the grading classification is of great value for the diagnosis,treatment and even prognosis of P-NETs.P-NETs are a group of malignant tumors with inert biological behaviors,whose surgical resection rate and long-term survival is much better than those of pancreatic ductal adenocarcinoma.P-NETs have different malignant potentials.Clinicians need to develop a comprehensive treatment plan in combination with the patient's symptoms,tumor grading classification and TNM staging information.Surgery is the only curable way to cure P-NETs.Even if radical resection is not suitable,palliative surgery may alleviate the patients,symptoms,and even prolong their survival time.According to the tumor location,size,quantity,degree of grading,local invasion and distant metastasis,different surgical procedures should be selected.