Protection of ovarian function for female breast cancer patients undergoing chemotherapy

VernacularTitle:女性乳腺癌患者化疗期间卵巢功能的保护
Author: Qingqing LUO ; Linjie LU ; Lingquan KONG ; Kainan WU
Keywords: Breast cancer; Protection of ovarian protection; Chemotherapy
From: Chinese Journal of Endocrine Surgery 2017;11(3):249-253
CountryChina
Language:Chinese
Abstract: Breast cancer is one of the most common malignant tumors in females.Recent years,surgery,chemotherapy as well as other systemic therapy had greatly improved the prognosis of the patients.However,damage of ovarian function by chemotherapy lowered life quality,especially for young females.At present,there are several methods to protect the ovarian function of female patients undergoing chemotherapy,such as administration of a gonadotropin-releasing hormone (GnRH) analogs,ovarian cryopreservation,unfertilized ova cryopreservation,embryo cryopreservation,inhibitors of apoptosis,etc.Each method has its advantage,disadvantage and indications.Issues related to ovarian protection are reviewed here.