Secondary metabolites from Aspergillus petrakii
10.3969/j.issn.1001-1528.2017.07.019
- VernacularTitle:佩特曲霉菌次生代谢产物的研究
- Author:
Yuling HUANG
;
Liying MA
;
Xianguo RONG
;
Deguo LI
;
Desheng LIU
;
Weizhong LIU
- Keywords:
Aspergillus petrakii;
secondary metabolites;
isolation and identification
- From:
Chinese Traditional Patent Medicine
2017;39(7):1415-1419
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the secondary metabolites from Aspergillus petrakii.METHODS The ethyl acetate extract liquid of A.petrakii fermentation broth was isolated and purified by silica,ODS,Sephadex LH-20 and RP-HPLC column,then the structures of obtained compounds were identified by spectral data and physicochemical properties.RESULTS Thirteen compounds were isolated and identified as R-(-)-mellein (1),3-(1-hydroxyethyl)-7-hydroxy-l-isobenzofuranone (2),(-)-semivioxanthin (3),endocrocin (4),p-hydroxyphenylethanol (5),p-hydroxyphenylacetamide (6),hydroquinone (7),adenosine (8),cyclo (Phe-Val) (9),cyclo (Phe-Ile) (10),cyclo (Tyr-Ala) (11),cyclo (Leu-Ile) (12),cyclo (Leu-Leu) (13).CONCLUSION All the compounds are isolated from A.petrakii for the first time.
