Value of aortic dissection detection risk score combined with D-dimer in patients with suspected acute aor-tic dissection
10.3969/j.issn.1006-5725.2017.13.038
- VernacularTitle:低主动脉夹层评分联合D-二聚体阴性对排除急性主动脉夹层诊断的价值
- Author:
Xiao YANG
;
Xia YANG
;
Hui XIE
;
Shiqiang WANG
;
Yujie LI
- Keywords:
aortic dissection detection risk score;
D-dimer;
acute aortic dissection
- From:
The Journal of Practical Medicine
2017;33(13):2213-2216
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the diagnostic value of combining aortic dissection detection risk score (ADDRS)with D-dimer in patients with suspected acute aortic dissection(AAD). Methods We retrospectively identified 525 patients with chest pain and with calculated ADDRS and available D-dimer on admission between January 2015 and December 2016. ADDRS ≤1 was defined as ′low probability′ and that >1 as ′high probability′. Results AAD were diagnosed in 106(20.2%)patients. In patients with ADDRS of 0,1 case of AAD was identi-fied and in those with ADDRS of 1,40 were identified while in 76 patients with ADDRS of 2 and 3,71 cases of AAD were identified. D-dimer with threshold of 0.5 mg/L had a negative predictive value of 100%and a specificity of 76.6% in patients with ADDRS of 0. In patients with ADDRS of 1,D-dimer had a negative predictive value of 98.6%. D-dimer showed a negative predictive value of 99.6% and a positive predictive value of 22.3% in patients with low probability. Conclusions High ADDRS benefits confirming AAD. Low ADDRS combined with negative D-dimer is safe and efficient for ruling out AAD ,while low ADDRS with positive D-dimer needs further aortic imaging.
