Feasibility and Accuracy for Evaluating Mitral Regurgitation Severity by General Imaging Three-dimensional Quantification
10.3969/j.issn.1000-3614.2017.07.009
- VernacularTitle:全身成像三维量化法评估二尖瓣反流严重程度的可行性及准确性
- Author:
Wugang WANG
;
Zhanbin WANG
;
Juan CONG
;
Junfang LI
;
Xiuxiu FU
;
Hao WANG
- Keywords:
Echocardiography;
three-dimentional;
Mitral valve insufficiency
- From:
Chinese Circulation Journal
2017;32(7):660-664
- CountryChina
- Language:Chinese
-
Abstract:
To explore the feasibility and accuracy for evaluating mitral regurgitation (MR) severity with MR jet volume (MRvol) by means of general imaging three-dimensional quantification (GI3DQ). Methods: A total of 93 MR patients were divided into 2 groups: Central MR group, n=41 and Eccentric MR group, n=52. According to real-time three-dimensional echocardiography (RT3DE) examined planimetry of effective regurgitation orifice area (EROA), the patients were graded into mild MR, moderate MR and severe MR. MRvol was directly measured by GI3DQ. Results: In Central MR group, ROC analysis showed that as GI3DQ measured MRvol>16.2 ml, AUC=0.93, P<0.0001, the sensitivity and specificity for distinguishing mild MR and moderate MR were 96.0% and 70.0%respectively; as MRvol>44.5 ml, AUC=0.96, P<0.0001, the sensitivity and specificity for distinguishing moderate MR and severe MR were 97.6% and 91.7% respectively. In Eccentric MR group, as MRvol>14.2 ml, AUC=0.77, P=0.0243, the sensitivity and specificity for differentiating mild MR and moderate MR were 91.8% and 62.5% respectively; as MRvol>40.5 ml, AUC=0.83, P<0.0001, the sensitivity and specificity for differentiating moderate MR and severe MR were 82.3% and 77.9% respectively. Conclusion: Taking RT3DE examined EROA as reference, GI3DQ directly measured MRvol could more accurately assess MR severity especially in patients with central MR, it may distinguish moderate MR and severe MR with the higher sensitivity and specificity.
