Relationship Between Plasma Calcium Level and Fibrinogen, Homocysteine in Non-diabetic Elderly Patients

VernacularTitle:非糖尿病老年人群血浆钙离子浓度与纤维蛋白原及同型半胱氨酸关系的研究
Author: Lei WANG ; Meng CAI ; Ping ZHANG
Keywords: Plasma calcium; Fibrinogen; Elderly
From: Chinese Circulation Journal 2017;32(7):689-691
CountryChina
Language:Chinese
Abstract: To explore the impact of normal range plasma calcium level changes on fibrinogen and homocysteine (Hcy) in non-diabetic elderly patients. Methods: A total of 1030 non-diabetic patients≥65 years were retrospectively studied. According to adjusted plasma calcium concentration (Cac), the patients were divided into 4 quartiles as Q1 group, Q2 group, Q3 group and Q4 group. The relationship between Cac and plasma levels of fibrinogen and Hcy were compared. Results: ① Plasma levels of fibrinogen and Hcy were increased by Cac elevation accordingly, P=0.010 and P<0.001 respectively. ② Cac was obviously related to the prevalence of high fibrinogen (OR=1.75, P=0.019) and high Hcy (OR=1.82, P=0.026). ③ Cac was positively related to fibrinogen (Standardized β=0.15, P<0.001) and Hcy (Standardized β=0.08, P=0.009). Conclusion: Normal range plasma calcium level changes were related to the elevation of plasma fibrinogen and Hcy in non-diabetic elderly patients.