Occupational Hepatic Disorders in Korea.
10.3346/jkms.2010.25.S.S36
- Author:
Hyoung Ryoul KIM
1
;
Tae Woo KIM
Author Information
1. Department of Preventive Medicine and Industrial Medical Center, The Catholic University of Korea, College of Medicine, Seoul, Korea. cyclor@catholic.ac.kr
- Publication Type:Review
- Keywords:
Dimethylformamide;
Trichloroethylene;
Drug-Induced Liver Injury;
Viral Hepatitis;
Health Care Workers
- MeSH:
Adult;
Drug-Induced Liver Injury/epidemiology;
Female;
Health Personnel;
Hepatitis, Viral, Human/epidemiology/prevention & control;
Humans;
Liver Diseases/*epidemiology/prevention & control;
Liver Neoplasms/chemically induced/epidemiology;
Male;
Middle Aged;
Occupational Diseases/*chemically induced/*epidemiology/prevention & control;
Occupational Exposure/adverse effects;
Republic of Korea/epidemiology;
Young Adult
- From:Journal of Korean Medical Science
2010;25(Suppl):S36-S40
- CountryRepublic of Korea
- Language:English
-
Abstract:
Occupational hepatic disorders are classified into toxic hepatitis, viral hepatitis, and chemical-induced malignancy in Korea. Toxic hepatitis cases were reported in workers who were exposed to dimethylformamide, dimethylacetamide, or trichloroethylene. Pre-placement medical examination and regular follow-up are necessary to prevent the development of toxic hepatitis. Viral hepatitis was chiefly reported among health care workers such as doctors, nurses and clinical pathology technicians who could easily be exposed to blood. Preventive measures for these groups therefore include vaccination and serum monitoring programs. Hepatic angiosarcoma caused by vinyl chloride monomer (VCM) exposure is a very well known occupational disease and it has not been officially reported in Korea yet. Some cases of hepatocellular carcinoma were legally approved for compensation as an occupational disease largely by overwork and stress, but not supported by enough scientific evidence. Effort to find the evidence of its causal relationship is needed.
