Observation of the application of fluorouracil sustained release implant in advanced gastric cancer surgery
10.3760/cma.j.issn.1008-6315.2017.07.023
- VernacularTitle:缓释氟尿嘧啶植入剂在进展期胃癌术中应用观察
- Author:
Jianshan LIU
;
Tiecheng BAI
;
Rongzeng LU
- Keywords:
Fluorouracil sustained release implant:intraperitoneal chemotherapy;
Advanced gastric cancer
- From:
Clinical Medicine of China
2017;33(7):659-663
- CountryChina
- Language:Chinese
-
Abstract:
Objective In recent years,as people have attached importance to the application of regional chemotherapy in the surgery of advanced gastric cancer,the research of fluorouracil sustained release implant,a regional chemotherapeutic drug,is on the increase.Fluorouracil sustained release implant is a new anti-carcinogen combined with fluorouracil,a conventional chemotherapeutic drug,through polymeric scaffolds and rete technology.It can be implanted into cancerous lesion area,as its slow-releasing potential and targeting property will give full play to the antitumor effect of fluorouracil,which can decrease the rate of local recurrence and metastasis of gastric cancer and prolong the life span of the patients.Based on the study of the researches on fluorouracil sustained release implant,a summary was made from different perspectives: basic medicine,pharmacy and clinical medicine.It may have reference value for clinical application and further study.
