The analysis of risk factors and subtypes with CISS classification of minor stroke
10.3969/j.issn.1002-0152.2017.06.003
- VernacularTitle:轻型卒中的病因分型和相关危险因素分析
- Author:
Xiaoyu CHEN
;
Sha TAN
;
Yanqiang WANG
;
Lei ZHANG
;
Xuehong HUANG
;
Ang LI
;
Zhengqi LU
- Keywords:
Minor stroke;
CISS;
Risk factors;
Triglyceride;
Apolipoprotein B;
apoB/apoA1;
C-reactive protein
- From:
Chinese Journal of Nervous and Mental Diseases
2017;43(6):331-335
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the features of risk factors of minor stroke with CISS classification in Guangdong Province. Methods We retrospectively investigated the patients admitted within 3 days of the occurrence of a minor stroke, and were classified by CISS criteria as large artery atherosclerosis (LAA), cardiogenic stroke (CS), penetrating artery disease (PAD), other etiology (OE), undetermined etiology (UE). Results In this study, 303 pa-tients met the inclusion criteria of minor stroke. The highest percentage of the risk factors included hypertension (72.3%), hyperlipidemia (58.3%), and diabetes mellitus (39.9%). Among different subtypes, 41.9% were diagnosed with LAA, and 50.8% with PAD. Plasma triglyceride (TG)(1.765 ±1.18)mg/L vs.(2.19 ±1.84)mg/L,P=0.03], apolipoproteinsB (ApoB) [(0.95±0.29)mg/L vs.(1.11±0.46)mg/L,P=0.009]C-reactive protein (CRP) [(6.63±11.30) mg/L vs.(3.42 ±5.02)mg/L,P=0.042] and ApoB/ApoA1 ratio [(0.754 ±0.25)mg/L vs.(0.875 ±0.49)mg/L,P=0.019], differed significantly between group LAA and PAD. Conclusion Hypertension, hyperlipidemia and diabetes mellitus are the major risk factors of minor stroke. The most common subtypes of the minor stroke patients in Guangdong Province are LAA and PAD, and detecting their TG, apoB, CRP level and apoB/apoA1 ratio might help subclassify minor stroke according to CISS.