Study on effect and mechanism of baicalin on antiviral effects about respiratory syncytial virus
10.3969/j.issn.1673-4130.2017.14.013
- VernacularTitle:黄芩苷抗呼吸道合胞病作用的研究
- Author:
Youchao ZHAN
;
Shen QIN
;
Fu CHEN
- Keywords:
baicalin;
antiviral;
respiratory syncytial virus;
interferon-α;
interferon-β
- From:
International Journal of Laboratory Medicine
2017;38(14):1907-1909
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the effect of the baicalin to the expression of interferon(IFN)-α and IFN-β in the BALB/c mouse infected by respiratory syncytial virus(RSV),and discussed the antiviral of mechanism.Methods To establish the BALB/c mouse model of RSV,the effects of IFN-α and IFN-β in the BALB/c mouse infected by RSV were detected by ELISA.Results The IFN-α and IFN-β in the BALB/c mouse infected by RSV could be evaluated significantly by Baicalin.Conclusion The Baicalin regulates the level of IFN in the BALB/c mouse infected by RSV.