Short-term and long-term efficacy of laparoscopic versus open liver resection in the treatment of hepatocel-lular carcinoma
10.3969/j.issn.1006-5725.2017.12.012
- VernacularTitle:完全腹腔镜和开腹肝切除手术治疗原发性肝细胞肝癌的近期和远期疗效比较
- Author:
Hao ZHANG
;
Ke DONG
;
Xiaojiong YU
;
Jian XU
;
Xu. WANG
- Keywords:
Laparoscopic liver resection;
Open liver resection;
Hepatocellular carcinoma
- From:
The Journal of Practical Medicine
2017;33(12):1943-1948
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the short-term and long-term efficacy of laparoscopic versus open liver resection(LLR)in the treatment of hepatocellular carcinoma(HCC). Methods The perioperative and follow-up data ofLLR(n = 43)and OLR(n = 73)for the treatment of HCC at the same period were analyzed respectively. Results There were no significant differences in the age,gender,Child-Pugh classification,liver cirrhosis, AFP,and hepatic virus affection between the 2 groups. 1 case in the LLR group was converted for the open surgery and another one case in the OLR group died in the perioperative time. However ,compared with OLR group ,the intraoperative blood loss of LLR group(P < 0.05)was larger and the mean operative time(P < 0.05)was longer. The liver function indicators of the regular hepatectomy subgroup were recovered more quickly(P<0.05),but the indicators of remaining subgroups were not significantly different. The postoperative ambulation time (P < 0.05), the postoperative eating time(P < 0.05),the postoperative hospital stay(P < 0.05)were all shorter. The VAS score was lower(P<0.05). There was no difference in the incidence and distribution of complications and the inci-dence of severe complications between the two groups(all P>0.05). The first and third year disease-free survival rates were 82.2%,53.8%for LLR and 91.5%,75.9%for OLR,respectively(χ2=0.55,P=0.46). The first and third 5 year overall survival rates were 94.2%,79.3%for LLR and 94.9%,47.3%for OLR,respectively(χ2=1.06, P=0.30). Conclusion LLR for HCC treatment is a safe and effective way with the advantages of minimal opera-tive trauma,quick recovery and significant short-term efficacy.
