ICSI cycle oocytes maturation ratio and different dosage of gonadotropin choices affecting embryo quality and clinical outcome
10.3969/j.issn.1006-5725.2017.12.022
- VernacularTitle:ICSI周期中不同卵母细胞成熟比例与促性腺激素用量的选择对胚胎质量及妊娠结局的影响
- Author:
Weirong ZENG
;
Guiyan YANG
;
Guifeng CAI
;
Yongming RUAN
;
Yonglao. XIONG
- Keywords:
Intracytoplasmic sperm injection;
Mature oocytes rate;
Gonadotrophin(Gn);
Clinical pregnancy rate
- From:
The Journal of Practical Medicine
2017;33(12):1982-1985
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore ICSI treatment process in the different proportion of oocytes maturation and dosage of gonadotropin affecting embryo quality and clinical outcome. Methods From Jan. to Dec. 2015,we retrospectively analyzed the patients from the center line of ICSI cycle ,divided them into three groups according to the maturity of oocytes. The 3 groups were due to maturity rate of oocytes in 50% in group A(n = 19),50% 0.05). Group A had the best egg rate,high quality embryo rate,clinical pregnancy rate than the other two groups (P < 0.05). In pregnancy and non-pregnancy groups ,the dosage of gonadotropin in the non-pregnancy group was obviously higher than that in the pregnancy group in oocyte maturation in the same proportion interval(P<0.05). Conclusion In ICSI treatment process,the high dose of gonadotropin and rising rates of oocytes maturation are not conducive to the development potential of the egg and clinical outcome,so the dose of gonadotropin and oocyte maturation ratio should be controlled in a certain range to collect and protect the best dominant egg which matches to the state of the patient.