Respiratory tract virus infection in dengue fever patients in Guangzhou
10.3969/j.issn.1006-5725.2017.12.040
- VernacularTitle:广州地区登革热病患呼吸道病毒感染情况
- Author:
Youchao ZHAN
;
Sheng. QIN
- Keywords:
Respiratory virus infection;
Dengue fever;
Epidemiology
- From:
The Journal of Practical Medicine
2017;33(12):2042-2045
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the respiratory tract virus infection in dengue fever patients in Guangzhou. Methods Totally 280 patients with dengue fever in 2014 and 32 patients from May to December 2015 were select-ed as group A and group B respectively. The distribution of clinical symptoms and signs ,age and onset time of the 2 groups were compared. Simultaneously ,other respiratory viruses in all patients were detected. Results In group B,the incidence of fever,bone pain,myalgia/body weight fatigue,anorexia,diarrhea,rash diagnosed and hemorrhage was higher than that in group A. The incidence difference of headache,bone pain,myalgia/body weight fatigue,anorexia and rash in 2 groups indicated no statistical significance(P > 0.05)but the incidence of anorexia was significantly different(P<0.05). In group A,there were a larger proportion of patients aged from 21to 30(28.57%)and from 31 to 40(25.36%)while in group B,there were a larger proportion of patients aged from 41 to 50 (19.69%) and from 51 to 65 (25.00%). There was no significant difference in the distribution of other age groups(P > 0.05)except that of 51 ~65 years in 2 groups(P < 0.05). In 2014,the peak inci-dence of dengue fever was in October (64.29%),followed by November (28.21%) and in 2015 ,October was the peak incidence of dengue fever (84.38%),followed by November (12.49%). The incidence in 2 groups in October was significantly different (P < 0.05). In 280 cases of group A ,positive rate of 9 respiratory virus was 30.36%(85/280) and there were 38 cases with MP (44.71%) and 24 with LP1 (27.24%);in 32 cases of group B ,positive rate of 9 respiratory virus was 32.50%(11/32) and there were 4 with MP (36.36%) and 3 LP1(27.27%). The detection rate of other viruses indicated no significant difference(P > 0.05). Conclusions The incidence of dengue fever is different in Guangzhou area at different time. The patients present different clinical symptoms and signs. Analysis of different pathogenic characteristics provides important basis for clinical treatment of dengue fever.