Clinical value of 99mTc-MDP SPECT/CT whole body bone imaging in diagnosis of bone metastasis of pros-tate cancer
10.3969/j.issn.1006-5725.2017.11.014
- VernacularTitle:99mTc-MDP SPECT/CT全身骨显像诊断前列腺癌骨转移的临床价值
- Author:
Feng ZHANG
;
Ju JIAO
;
Liangjun XIE
- Keywords:
Prostate cancer;
Bone metastasis;
Single photon emission tomography;
Image fusion
- From:
The Journal of Practical Medicine
2017;33(11):1774-1777
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of 99mTc-MDP SPECT/CT whole body bone imaging in the diagnosis of bone metastasis of prostate cancer. Methods A total of 107 cases with prostate cancer were di-agnosed by SPECT whole body bone imaging from January 2013 to November 2016. SPECT/CT imaging of some ab-normal density collective focus found in whole body bone imaging were further carried out. Six months later ,whole body bone imaging and SPECT/CT were made again for review. In all diagnosis above ,99mTc-MDP were selected as bone imaging agent. According to the results of follow-up visit clinical and imaging diagnosis ,diagnostic perfor-mance indicators of whole body bone imaging and SPECT/CT were calculated. Results The different part of whole body bone imaging and SPECT/CT in the diagnosis of bone metastases was statistically significant(x2 = 23.000, P < 0.001). The diagnosis specificity and coincidence rate of SPECT/CT for bone metastasis were 100.0% and 98.1% respectively and they were significantly higher than those of whole body bone imaging(65.0% and 80.4%respectively). The differences were statistically significant(P < 0.05). After SPECT/CT diagnosis,a total of 193 undetermined lesions were found and 83 lesions of these were final diagnosed of bone metastases. Pelvic lesions were most in bone metastases ,accounting for 50.6%. Conclusion Whole body bone imaging can effectively determine the undetermined lesions , further SPECT/CT can significantly improve the diagnostic accuracy of prostate cancer bone metastasis.
