Rectum-preserving surgery in the era of neoadjuvant chemoradiotherapy
10.3760/cma.j.issn.1673-9752.2017.07.005
- VernacularTitle:新辅助放化疗时代的保直肠手术现状与前景
- Author:
Pan CHI
;
Yanwu SUN
- Keywords:
Rectal neoplasms;
Neoadjuvant chemoradiotherapy;
Organ preserving surgery
- From:
Chinese Journal of Digestive Surgery
2017;16(7):662-667
- CountryChina
- Language:Chinese
-
Abstract:
Neoadjuvant chemoradiotherapy (nCRT)and subsequent radical resection have become the standard care of locally advanced rectal cancer (LARC).However,conventional radical surgery is associated with high intra-and postoperative morbidities,and a temporary or permanent stoma in some cases,impaired sexual and urinary function,and it eventually impair the quality of life.Rectum-preserving surgery is a novel concept in the era of nCRT,which will maximally benefit patients through the minimized injuries.This strategy has been increasingly utilized in LARC following nCRT.Nevertheless,it lacks high-level evidence of evidence-based medicine,and the long-term oncological safety remains to be determined by larger,multicenter,randomized clinical trials.The crucial aspect of rectum-preserving surgery is to accurately evaluate the status of primary tumor and metastatic lymph nodes,and thus to selective patients who could benefit from this strategy most.
