Anti-tumor immunity and mechanism of microwave ablation
10.3760/cma.j.issn.1673-4203.2017.06.020
- VernacularTitle:微波消融的抗肿瘤免疫效应及其机制研究进展
- Author:
Li LI
;
Mengdi LIANG
;
Wenbin ZHOU
;
Shui WANG
- Keywords:
Microwaves;
Ablation techniques;
Neoplasms;
Immunity;
Antigens,neoplasm
- From:
International Journal of Surgery
2017;44(6):429-432
- CountryChina
- Language:Chinese
-
Abstract:
Microwave ablation,as a minimally invasive therapy,causes focal hyperthermic injury to ablated tumors.It also induces anti-tumor immunity which could contribute to another mechanism of tumor destruction.Combination with immunotherapy could further enhance the tumor-specific immunity,lead to stronger inhibitory effects on both primary and metastatic lesions and decrease recurrence and metastasis.Thus,combination of microwave ablation and immunotherapy is a promising approach in the treatment of solid tumors,especially for advanced cancers.This article reviews recent advances in the mechanism and application of immune effect induced by microwave ablation.