The Relationship between stroke location and post-stroke depression in first-ever stroke patients:a Meta-analysis
10.3969/j.issn.1671-8348.2017.19.025
- VernacularTitle:首次卒中患者卒中部位与卒中后抑郁相关性的Meta分析
- Author:
Zunjia WEN
;
Chao WU
;
Meifen SHEN
;
Binbin MEI
;
Jianping DING
- Keywords:
stroke;
depression;
stroke location;
correlation;
Meta-analysis
- From:
Chongqing Medicine
2017;46(19):2677-2682
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the relationship between stroke location and post-stroke depression (PSD) in first-ever stroke patients.Methods The studies on the relationship between stroke location and PSD published from January 1980 to March 2016 were retrieved from databases,including Chinese science and technology journal full-text database (VIP),China journal full-text database (CNKI),Wanfan database,PubMed,ISI Web of Science,Ovid database and Elsevier Science Direct.RevMan5.3 software was adopted for data consolidation and analysis.Results A total of 14 studies,including 1 952 cases of patients were included.The meta analysis indicated that no direct relationship was found between stroke location and PSD in first-ever stroke patients [random effects model,95 ％CI(0.89,1.43),P＜0.01].The results of subgroup analysis indicated that the PSD was associated with the right hemisphere lesion when the Hamilton Depression Scale (HAMD) was adopted for assessment [fixed effects model,95 ％ CI(1.21,1.76),P＜0.01],while the relationships were not found in the subgroup analysis of time course after stroke and the aphasia occurrence.Conclusion Stroke location may be not directly associated with PSD,further studies are needed to ascertain the relationship between stroke location and PSD.
