Recent advances in treatment of Leber's hereditary optic neuropathy
10.13389/j.cnki.rao.2017.0174
- VernacularTitle:Leber遗传性视神经病变的治疗进展
- Author:
Jun CHEN
;
Yi DU
;
Jianfeng HE
- Keywords:
Leber's hereditary optic neuropathy;
idebenone;
EPI-743;
brimonidine;
traditional Chinese medicine;
gene therapy;
physician therapy
- From:
Recent Advances in Ophthalmology
2017;37(7):684-687
- CountryChina
- Language:Chinese
-
Abstract:
Leber's hereditary optic neuropathy (LHON) is an inherited mitochondrial disorder characterized by bilateral progressive vision loss.Current management includes therapies directed at enhancing mitochondrial function and preventing oxidative damage.This article reviews the progress of treatments from mitochondria cocktail,idebenone,gene therapy,EPI-743,brimonidine,traditional Chinese medicine and physical therapy,providing a new insight in the treatments of LHON.
