Research progress on cancer stem cells in ocular malignancy
10.13389/j.cnki.rao.2017.0176
- VernacularTitle:肿瘤干细胞在眼部恶性肿瘤中的作用
- Author:
Lei ZHENG
;
Jiamin WEN
;
Guoming ZHANG
- Keywords:
cancer stem cells;
ocular malignancy;
metastasis;
recurrence
- From:
Recent Advances in Ophthalmology
2017;37(7):692-696
- CountryChina
- Language:Chinese
-
Abstract:
Cancer stem cells (CSCs) are a small subset of cancer cells in the tumor,which possess the exclusive ability to proliferate indefmitely and multiple differentiation.These tumor cells play a crucial role in the maintenance of malignant proliferation,drug resistance,metastasis and recurrence.Majority of ocular malignancies have the properties of high recurrence,metastasis and poor prognosis.Recently,CSCs was found to exist in the ocular malignancies,also might be involved in the tumor initiation and progression.This article reviews the research progress on CSCs in ocular malignancy.
