Prevalence and risk factors of silent brain infarcts in the population based Shunyi Study
10.3760/cma.j.issn.1006-7876.2017.07.008
- VernacularTitle:顺义社区人群无症状性脑梗死的患病率及危险因素
- Author:
Fei HAN
;
Feifei ZHAI
;
Lixin ZHOU
;
Jun NI
;
Ming YAO
;
Shuyang ZHANG
;
Liying CUI
;
Mingli LI
;
Zhengyu JIN
;
Yicheng ZHU
- Keywords:
Stroke;
Prevalence;
Risk factor;
Population based study
- From:
Chinese Journal of Neurology
2017;50(7):515-519
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence and cardiovascular risk factors of silent brain infarct (SBI) in Shunyi Cohort.Methods This study was based on the population based Shunyi Study in China.One thousand and twenty-seven stroke-free participants older than 35 years,who completed cerebral MRI,were included.Cardiovascular risk factors were assessed by interview,physical examination and blood sample tests.SBI was evaluated on 3D-T1WI,T2WI and FLAIR sequences.Associations between risk factors and SBI were analyzed by Logistic regression and adjusted for age,sex,and relevant confounders.Results One thousand and twenty-seven participants,aged (55.9 ± 9.4) years,37.7％ male,were assessed.One hundred sixty-four participants(16.0％) had SBI on MRI.The prevalence of SBI increased by age (every 10 years,OR=2.12,95％ CI 1.74-2.58,P＜0.01).Hypertension(OR =2.67,95％ CI 1.77-4.04,P＜0.01),diabetes(OR=2.48,95％ CI 1.64-3.76,P＜0.01) and smoking(OR=1.98,95％ CI 1.08-3.62,P =0.028) were significantly associated with SBI.Conclusions The prevalence of SBI in this Chinese population is 16.0％,which increases with age.Hypertension,diabetes and smoking are associated with SBI.
