Clinical pathological characteristics and prognosis of neuroendocrine tumors of the appendix

VernacularTitle:阑尾神经内分泌肿瘤的临床病理特征与预后分析
Author: Yingze XIAO ; Dongjie BAN ; Dan WANG ; Jianming WEI
Keywords: Neuroendocrine tumors; Appendical neoplasms; Pathology,clinical; Prognosis
From: Chinese Journal of General Surgery 2017;32(6):477-480
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical pathological characteristics and prognostic factors of patients with neuroendocrine tumor of the appendix.Methods Data of 42 cases of the appendiceal neuroendocrine tumor from June 2006 to June 2016 at Tianjin Police Hospital were analyzed.Tumors were classified according to 2010 WHO classification.The survival curves were drawn using Kaplan-Meier method.Univariate analysis was performed by the Log-rank test.Results There were 27 males and 15 females,with median age of 60 years.Tumors located in the head of the appendix in 37 cases,in the body in 2 cases and at the base in 3 cases.The median of tumor sizes were 1.2 cm.G1 in 17 cases,G2 in 21 cases,G3 in 4 cases.The follow-up rate was 100％.The overall 1-year survival rate was 92％.Conclusions The clinical symptoms of appendiceal neuroendocrine tumors are most often nonspecific.The diagnosis depends on pathological examination and immunohistochemistry,and prognosis varies with pathological grades.