Mechanism of RhoA and its progress in gastric cancer
10.3760/cma.j.issn.1006-9801.2017.07.019
- VernacularTitle:RhoA的作用机制及其在胃癌中的研究进展
- Author:
Mengmeng WU
- Keywords:
Gastric neoplasms;
Rho-associated kinases;
Invasion;
Metastasis
- From:
Cancer Research and Clinic
2017;29(7):494-498
- CountryChina
- Language:Chinese
-
Abstract:
The morbidity and mortality of gastric cancer is high all over the world, while less specific target of gastric cancer has been found. RhoA is highly expressed in gastric cancer, which is closely related to tumor invasion and metastasis. An increasing evidence has showed that RhoA is a potential target for gene therapy of gastric cancer, and it can predict the invasion and metastasis of tumor cells. This paper reviews the mechanism of RhoA and research progress in gastric cancer.
