Progress on roles and mechanisms of CCAAT/enhancer binding protein β in endometrium decidualization
10.3969/j.issn.1674-8115.2017.06.026
- VernacularTitle:转录因子C/EBPβ在子宫蜕膜化中的作用及机制研究进展
- Author:
Fangfang DI
;
Jiansheng LIU
;
Shang LI
;
Yanzhi DU
- Keywords:
CCAAT/enhancer binding protein β;
endometrial stromal cell;
decidualization;
proliferation;
differentiation;
cell cycle
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2017;37(6):865-869
- CountryChina
- Language:Chinese
-
Abstract:
CCAAT/enhancer binding protein β (C/EBPβ) is a critical member of C/EBP family.C/EBPβ,based on the leucine zipper located in C terminal of the protein,can regulate transcriptional activities of downstream target genes involved in diverse cellular processes,such as proliferation and differentiation.Recently published studies have identified that C/EBPβ is essential in the decidualization of endometrial stromal cells.This review summarizes the roles and mechanisms of C/EBPβ during the courses of decidualization,which is aimed at providing novel insights for dysfunctional decidualization.
