Role of local immune microenvironment of lung lesion in Mycobacterium tuberculosis infection
10.3760/cma.j.issn.0254-5101.2017.08.014
- VernacularTitle:肺组织免疫微环境在机体抗结核分枝杆菌感染免疫中的作用
- Author:
Zhidong HU
;
Xiaoyong FAN
- Keywords:
Mycobacterium tuberculosis;
Immune response;
Immune microenvironment
- From:
Chinese Journal of Microbiology and Immunology
2017;37(8):634-639
- CountryChina
- Language:Chinese
-
Abstract:
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (Mtb) infection,remains a major global concern.The activation of anti-TB immune responses is mediated by several complicated mechanisms, among which the local immune microenvironment at the disease site plays a crucial role.In this review, we discuss the roles of anti-TB immunity, Mtb immune escape and the elements at the local site of infection.