Relationship Between Prevalence of Atrial Fibrillation, Ischemia Stoke and CHA2DS2-VASc Score in Elderly Patients
10.3969/j.issn.1000-3614.2017.05.008
- VernacularTitle:老年心房颤动患病率与缺血性卒中及CHA2DS2-VASc评分的相关性
- Author:
Li WANG
;
Qingwei CHEN
;
Qin FENG
;
Dazhi KE
;
Guiqiong LI
- Keywords:
Atrial fibrillation;
Risk factors;
Stroke;
CHA2DS2-VASc score
- From:
Chinese Circulation Journal
2017;32(5):452-456
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the relationship between prevalence of atrial fibrillation (AF), iskhemia stoke and CHA2DS2-VASc score in patients≥65 years in order to provide prevention and treatment basis in clinical practice. Methods: A total of 5016 patients admitted in our hospital from 2013-10 to 2015-10 were enrolled. The patients were divided into 2 groups: AF group, n=437 and Non-AF patients, n=4579; according to age, the patients were further assigned into 4 subgroups as <65 years subgroup, (65-74) years subgroup, (75-84) years subgroup and ≥85 years subgroup. The risk factors for AF occurrence were retrospectively studied. Results: Compared with the Non-AF group, the patients in AF group had the elder age and more male gender, both P<0.001; more patients combining with hypertension, coronary artery disease (CAD), diabetes, sick sinus syndrome and rheumatic heart disease, all P<0.001. Age, male gender, CAD, sick sinus syndrome and rheumatic heart disease were the independent risk factors for AF occurrence. Compared with Non-AF group, AF group showed the higher prevalence rate of ischemic stroke and the elder onset age, both P<0.01. For non-valvular AF, the ratio of patients with CHA2DS2-VASc score≥2 was higher than those with CHA2DS2-VASc score<2 and the rate of anticoagulant therapy was decreasing by age increasing, all P<0.001. Conclusion: Age, male gender, CAD, sick sinus syndrome and rheumatic heart disease were independently related to AF occurrence. Non-valvular AF patients had the higher risk for ischemic stroke than non-AF patients, anticoagulation therapy should be conducted at the early stage.
