Research advances on the role of long non-coding RNA in myocardial reperfusion injury
10.3760/cma.j.issn.1673-4904.2017.06.024
- VernacularTitle:长链非编码RNA在心肌缺血再灌注损伤中的研究进展
- Author:
Xiaoling PANG
;
Qian WANG
;
Xianbin CAI
;
Jie ZHU
- Keywords:
Myocardial reperfusion injury;
Apoptosis;
Long non-coding RNA;
Oxygen free radical;
Calcium overload
- From:
Chinese Journal of Postgraduates of Medicine
2017;40(6):564-567
- CountryChina
- Language:Chinese
-
Abstract:
Long non-coding RNA plays an increasingly important role in transcriptional, post-transcriptional and epigenetic levels. In ischemic heart disease, most studies on long non-coding RNA focused on myocardial infarction, hypertrophy and fibrosis, and a few of reports directly focused on the pathological process of myocardial reperfusion injury. Thus, the purpose of this review is to introduce the processes of long non-coding RNA in myocardial reperfusion injury field, aiming to provide a novel research and theraputic method for exploring the mechanism and molecular regulation network involed with reperfusion injury.
