Progress of the application of stem cell therapy for end-stage liver disease
10.11817/j.issn.1672-7347.2017.04.015
- VernacularTitle:干细胞治疗终末期肝病的进展
- Author:
Xingxiang DUAN
;
Yang WANG
;
Jingjing HE
;
Yingying PENG
;
Juan YU
;
Yi SUN
- Keywords:
stem cells;
end-stage liver disease;
differentiation;
cell transplantation
- From:
Journal of Central South University(Medical Sciences)
2017;42(4):457-462
- CountryChina
- Language:Chinese
-
Abstract:
Many risk factors lead to hypohepatia and hepatic failure,causing people suffering from end-stage liver disease.The conventional treatment for end-stage liver disease is not good enough.Orthotopic liver transplantation is effective.However,the high cost,lack of liver source,immune rejection and other factors limit the large-scale clinical application.Thus,cell therapy is a good option.Studies on common cell sources for the treatment of liver disease and the induction of hepatocytes by embryonic stem cells or pluripotent stem cells have made progress.With the development of stem cell technology,cell transplantation has become a new option,which brings hope to people with end-stage liver diseasetransplantation has become a new option.It brings hope to people with endstage liver disease.
