Predictive value of NT-proBNP and HCY in patients with essential hypertension complicating left ventricular hypertrophy
10.3969/j.issn.1673-4130.2017.09.003
- VernacularTitle:NT-proBNP和HCY对原发性高血压患者合并左心室肥厚的预测价值
- Author:
Yahong NIE
;
Rong ZHANG
;
Lei ZHANG
;
Xiaofeng MU
- Keywords:
essential hypertension;
left ventricular hypertrophy;
N-terminal pro-brain natriuretic peptide;
homocysteine
- From:
International Journal of Laboratory Medicine
2017;38(9):1160-1162
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the levels of blood N-terminal pro-brain natriuretic peptide(NT-proBNP) and homocysteine(HCY) and their clinical significance in the patients with essential hypertension(EH) complicating left ventricular hypertrophy(LVH).Methods One hundred and fifty cases of HE were divided into the EH-LVH group and simple EH group according to the results of cardiac ultrasound.One hundred individuals undergoing physical examination were selected as the control group.The levels of blood NT-proBNP and HCY were compared among three groups and the correlation analysis were analyzed with LV was performed.Results The levels of blood NT-proBNP and HCY in the EH-LVH group were obviously higher than those in the EH group and control group,the EH group was significantly higher than the control group,the difference was statistically significant(P<0.05).The levels of blood NT-proBNP and HCY had significantly positive correlation with left ventricular mass index(LVMI),while negative correlation with mitral flow velocity E/A(P<0.05).Conclusion The NT-proBNP and HCY levels can be used as the indicators for monitoring the development and progress of EH and has some predictive value for its complicating LVH.
