Application of nucleoprotein immature sperm percentage and sperm DNA damage rate detection in in vitro fertilization
10.3969/j.issn.1673-4130.2017.11.005
- VernacularTitle:精子DNA碎片率与精子核蛋白不成熟度检测在体外受精治疗中的应用研究
- Author:
Shuyuan LIU
;
Jianhong WEI
;
Junye HUO
;
Yuqi LAI
- Keywords:
in vitro fertilization;
optimal embryo rate;
sperm DNA damage;
sperm nucleoprotein immaturity rate
- From:
International Journal of Laboratory Medicine
2017;38(11):1452-1453,1456
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application value of sperm nucleoprotein immaturity and sperm DNA damage detection in in vitro fertilization(IVF).Methods From Mar.2015 to Feb.2016,routine sperm analysis,sperm nucleoprotein immaturity and sperm DNA damage detection were performed in 102 patients with infertility,and the correlation between these parameters were analyzed.Results Sperm DNA fragmentation rate was negatively correlated with IVF optimal embryos rate and sperm viability(P<0.05),while was not correlated with IVF fertility rate(P>0.05).Sperm nucleoprotein immaturity rate was not correlated with IVF optimal embryos rate and fertility rate(P>0.05),while was negatively correlated with sperm concentration(P<0.05).Conclusion Sperm DNA fragmentation rate could be closely correlated with IVF optimal embryos rate,which might be with prediction value in IVF treatment.
