Effect of mifepristone on early ectopic pregnancy and its effect on fertility
10.3969/j.issn.1005-1678.2017.09.152
- VernacularTitle:米非司酮治疗早期异位妊娠的有效性及对患者生育力的影响
- Author:
Lili ZHANG
;
Haiqing LAI
- Keywords:
mifepristone;
methotrexate;
early ectopic pregnancy;
effectiveness;
fertility
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(9):341-343
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of mifepristone in the treatment of early ectopic pregnancy and its effect on the fertility of patients. Methods 90 patients with early ectopic pregnancy admitted in our hospital from January 2011 to December 2012 were randomly divided into two groups. The control group was treated with methotrexate. The combination group was treated with mifepristone. Patient treatment effectiveness and fertility. Results There were no significant differences in β-HCG (human chorionic gonadotropin) and mass in the two groups before treatment. After treatment, the patients were significantly improved, the study group was significantly better than the control group (P<0.05). The rate of intrauterine pregnancy was significantly higher in the study group than that in the control group (P<0.05). The rate of ectopic pregnancy and secondary infertility were significantly lower than those of the control group (P<0.05 ). The incidence of adverse reactions in the study group was lower than that in the control group (P<0.05). Conclusion The efficacy of mifepristone in the treatment of early ectopic pregnancy is ideal for the retention of patient fertility and should be promoted.
