Effect of Liujunzi soup on allergic cough in remission stage and total inflammation of children
10.3969/j.issn.1005-1678.2017.09.036
- VernacularTitle:六君子汤治疗缓解期过敏性咳嗽对患儿总病程及炎性介质的影响
- Author:
Jingdong LU
;
Jing QIU
- Keywords:
Liujunzi soup;
remission period;
allergic cough;
total course;
inflammatory mediators
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(9):91-93
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of Liujunzi soup on the total course of disease and inflammatory mediators in patients with remission of allergic cough. Methods Eighty six patients with allergic cough were enrolled in our hospital from April 2011 to April 2012. The patients were randomly divided into observation group (n = 43) and control group (n = 43). The control group was given basic western medicine treatment, the observation group in the control group on the basis of another treatment of six gentleman soup. The levels of inflammatory cytokines, pulmonary function and adverse reactions were compared between the two groups in clinical efficacy, hospitalization time, total course of disease, IL-2, TNF-α and IL-6. Results The total effective rate was 90.70％ in the observation group was significantly higher than that in the control group (72.09％)( P<0.05). The duration of hospitalization (13.35 ± 3.24) d and the total course of disease (17.68 ± 4.53) d were significantly shorter than those in the control group (16.23 ±3.10) d, (20.35 ± 4.67) d (P<0.05). The levels of inflammatory factors and pulmonary function in the observation group were statistically significant compared with the control group (P<0.05). No adverse reactions occurred in both groups. Conclusion Liujunzi Decoction combined with western medicine can improve the level of inflammatory cytokines and lung function, shorten the length of hospital stay, the total course of disease and high safety, and have good clinical value.
