Clinical effect of methotrexate combined with dilatation and curettage treatment on the treatment of cesarean section scar pregnancy and the effect on HCG

VernacularTitle:甲氨喋呤联合清宫术治疗剖宫产瘢痕妊娠的临床疗效及对患者HCG影响
Author: Zhengwen CHEN ; Qiaodan JIN ; Feng QI ; Zeying CHAI
Keywords: methotrexate; dilatation and curettage; cesarean scar pregnancy; human chorionic gonadotropin
From: Chinese Journal of Biochemical Pharmaceutics 2017;37(9):194-195,197
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical effect of methotrexate combined with dilatation and curettage on the treatment of cesarean section scar pregnancy and the effect on HCG (chorionic gonadotropin). Methods 130 cases with cesarean section scar pregnancy admitted in Taizhou hospital from January 2016 to March 2017 were randomly divided into two groups. The control group wasreceived dilatation and curettage. The study group was given methotrexate combined with dilatation and curettage.The effect and the influence to HCG in the two groups were compared. Results The effective rate in the study group was significantly higher than that in the control group (P<0.05). There was no significant difference in HCG level between the two groups before treatment. The levels of HCG in the study group were significantly lower than that in the control group (P<0.05). Conclusion Methotrexate combined with curettage on the treatment of cesarean scar pregnancy, can improve the therapeutic effect, reduce postoperative bleeding and hospitalization time, reduce the level of HCG.