Clinical efficacy of somatostatin combined with ulinastatin in the treatment of upper gastrointestinal hemorrhage and its effects on IL-2, IL-6 and TNF-α

VernacularTitle:生长抑素联合乌司他丁治疗上消化道出血患者的临床疗效及对IL-2、IL-6及TNF-α水平的影响
Author: Qianqian LI
Keywords: somatostatin; ulinastatin; digestive tract hemorrhage; enzyme linked immunosorbent assay
From: Chinese Journal of Biochemical Pharmaceutics 2017;37(9):273-274,277
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical efficacy of somatostatin combined with ulinastatin in patients with upper gastrointestinal bleeding and the effects of interleukin -2 (IL-2), interleukin -6 (IL-6) and tumor necrosis factor (TNF-). Methods From May 2015 to June 2017, 90 patients with gastrointestinal bleeding were treated in the first people's hospital in Wenling, which were divided into the control group (n=45) and the observation group (n=45) by random number method. The control group was treated with simple somatostatin, and the observation group was treated with ulinastatin on the basis of the control group. Results The curative effect in the observation group was significantly better than that in the control group (P<0.05). Conclusion Somatostatin combined with ulinastatin in the treatment of patients with upper gastrointestinal bleeding is effective and helpful to improve the levels of IL-2, IL-6 and TNF- alpha, so it is worthy of popularization and application.