Effect analysis of combined treatment with multiple drugs on upper gastrointestinal bleeding in emergency internal medicine
10.3969/j.issn.1005-1678.2017.09.171
- VernacularTitle:多种药物综合治疗急诊内科上消化道出血的效果分析
- Author:
Rongyuan SUN
;
Wanjie YANG
;
Liping SUN
;
Bowen ZHANG
;
Yingjie XU
;
Rui ZHANG
- Keywords:
emergency treatment;
GI Medicine;
hemorrhage of upper digestive tract;
combined treatment;
clinical effect
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(9):384-386
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of combined treatment of upper gastrointestinal bleeding in emergency internal medicine. Methods A total of 102 patients with upper gastrointestinal bleeding were enrolled in the Department of Emergency Gastroenterology, Peking Binhai University Hospital from June 2014 to October 2016. The patients were randomly divided into observation group and control group, 51 cases in each group.The control group were only given omeprazole sodium, tranexamic acid injection,the observation group were given Agkistrodon hemocoagulase for injection on patients on the basis of the control group.After treatment, the clinical curative effect of two groups of patients were evaluated, the hospitalization days, the average hemostasis time, blood transfusion, bowel recovery time, abdominal pain relief time, the adverse reactions occurred of the two groups were observed.Results The total effective rate of the observation group was significantly higher than that of the control group (P< 0.05). The hemostasis time,the time of hospitalization and the average blood transfusion in the observation group were significantly lower than those in the control group (P<0.05). The recovery time of bowel and the time of pain relief in the observation group were significantly lower than in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the observation group and the control group.Conclusion Comprehensive treatment of upper gastrointestinal bleeding with emergency internal medicine can significantly improve the clinical efficacy, shorten the time of hemostasis and recovery, and is worthy of clinical application.
