Comparative study of ELISA in the detection of antibodies to hepatitis C virus

VernacularTitle:酶联免疫吸附试验检测丙型肝炎抗体的可比性研究
Author: Yaner YU ; Xiaoling ZHUANG
Keywords: hepatitis C antibodies; enzyme-linked immunosorbent assay; colloidal gold method; application effect
From: Chinese Journal of Biochemical Pharmaceutics 2017;37(9):425-426
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical effect of enzyme linked immunosorbent assay (ELISA) in detecting hepatitis C antibody. Methods 200 cases of patients with hepatitis C was measured by ELISA, the gold standard method for detection of hepatitis C virus antibody, recording the test results, the data input SPSS software to give the corresponding analysis and conclusions. Results 200 cases of patients with hepatitis C were successfully completed the gold standard method and ELISA method for detection of hepatitis C virus antibody, the analysis showed that positive rate of ELISA method for detection of hepatitis C virus antibody was significantly higher than that of the gold standard method, the positive rate of ELISA was 82.50％, the positive rate of the gold standard method for was 50.00％, results suggested that HCV detection rate of ELISA method is significantly better (P<0.05). Conclusion The method of ELISA can be used for the detection of hepatitis C antibody, which has positive significance in improving the diagnostic accuracy of hepatitis C, and is beneficial to protect the efficacy and quality of life of patients.