Four changes of plasma D- dimer and coagulation in pregnant women at different stages of pregnancy and their value of test

VernacularTitle:孕妇妊娠不同时期血浆D-二聚体和凝血四项变化及其检验价值分析
Author: Xin ZENG ; Xia YUAN
Keywords: pregnancy; different periods; plasma D- dimer; blood coagulation four; test value
From: Chinese Journal of Biochemical Pharmaceutics 2017;37(9):429-430
CountryChina
Language:Chinese
Abstract: Objective To observe and analyze the four changes of plasma D- dimer and coagulation in pregnant women at different stages of pregnancy, and to explore the value of the test. Methods The subjects of this study were 120 pregnant women who underwent routine physical examination in our hospital, according to different stages of pregnancy (early pregnancy, middle pregnancy, late pregnancy, and before delivery) Four D- dimer and four blood coagulation tests were performed in pregnant women, and the results were observed and compared. Results During the pregnancy, D- dimer has increase trend (P<0.05); early in pregnancy, pregnancy and late pregnancy, PT has shortened(P<0.05); pregnancy, APTT has shortened (P<0.05), at the end of pregnancy and parturient period, showing a significant shortening (P<0.05); phenomenon in early pregnancy to mid pregnancy stage, FIB increased significantly (P<0.05), and at the end of pregnancy to perinatal period, with a sharp increase (P<0.05). Conclusion It is of great significance to perform dynamic monitoring of of plasma D- dimer and coagulation four indices in pregnant women during pregnancy.