Clinical analysis of rhabdomyolysis syndrome caused by alcohol withdrawal syndrome

VernacularTitle:酒精戒断综合征致横纹肌溶解的临床分析
Author: Qiang ZHONG ; Li GONG ; Hongqian HE
Keywords: Substance withdrawal syndrome; Rhabdomyolysis; Creatine kinase; Myoglobin; Retrospective studies
From: Chinese Journal of Postgraduates of Medicine 2017;40(9):800-802
CountryChina
Language:Chinese
Abstract: Objective To analyze the characteristics of rhabdomyolysis (RM) caused by alcohol withdrawal syndrome (AWS). Methods The clinical data of 7 patients with RM induced by AWS were analyzed retrospectively. Results All 7 patients were male;the age was 38-63 (51.3 ± 9.8) years. All of the 7 patients showed obvious myalgia and fatigue, of whom 4 patients had limb swelling, and 3 patients had epigastric pain. Creatine kinase and myoglobin levels of 7 cases were significantly increased. One case had acute renal failure. Seven patients were improved after treatment with a large amount of fluid infusion. Conclusions For patients with AWS who have generalized withdrawal seizures and epileptic seizures, muscle cells can be damaged due to prolonged muscle contraction, which can cause RM. Changes of myoglobin, creatine kinase, renal function and liver function in patients with AWS should be monitored at clinical admissions. If RM occurs, the patients should be given early fluid therapy.