Efficacy of laparoscopy-assisted radical gastrectomy for elderly patients with gastric cancer
10.3969/j.issn.1000-8179.2017.16.436
- VernacularTitle:腹腔镜辅助胃癌根治术对老年胃癌患者的临床疗效分析
- Author:
Kai XU
;
Ming CUI
;
Jiadi XING
;
Hong YANG
;
Chenghai ZHANG
;
Lei CHEN
;
Zhendan YAO
;
Nan ZHANG
;
Maoxing LIU
;
Xiangqian SU
- Keywords:
laparoscopy;
elderly;
gastric cancer;
complication survival
- From:
Chinese Journal of Clinical Oncology
2017;44(16):800-804
- CountryChina
- Language:Chinese
-
Abstract:
Objective: This study aimed to compare the short- and long-term outcomes of laparoscopy-assisted radical gastrectomy between elderly and non-elderly patients with gastric cancer. Methods: A total of 219 patients who underwent laparoscopy-assisted radical gastrectomy in the Department of Gastrointestinal Surgery IV, Peking University Cancer Hospital & Institute from April 2009 to October 2013 were included in this retrospective study. All patients were divided into elderly (≥65 years) and non- elderly (<65 years)groups. We compared these groups based on clinicopathological characteristics, postoperative morbidities, and survival. Results:Theelderly group showed higher ASA scores and higher number of preoperative comorbidities (P<0.05). The operative time, blood loss,and conversion rate did not differ significantly between the groups (all P>0.05). The mean time to first ambulation in elderly group was 2.2±2.3d while first ambulation time in the non-elderly group was 1.4±1.3d,which showed significant difference between the two groups (P<0.05). No significant differences were observed between groups in terms of postoperativemorbidities (34.8％ vs. 28.5％, P> 0.05) as well as 3-year disease-free survival and overall survival (P>0.05). However, the elderly patients withpostoperative morbidities experienced significantly poorer overall survival rate than non-elderly patients (44.5％ vs. 70.5％, P<0.05). Conclusion: Laparoscopy-assisted gastrectomy can be safely and successfully performed in an elderly population with acceptable short- and long-term outcomes.Enhanced perioperative treatment is necessary to improve postoperative outcomes.
