Characteristic of cerebrovascular pathological changes in cerebral infarction patients accompanied with hyperhomocysteinemia
- VernacularTitle:高同型半胱氨酸血症型高血压患者脑血管病变特点
- Author:
Fei LU
- Keywords:
hyperhomocysteinemia with hypertension;
digital subtractiona angiography;
cerebral infarction
- From:
Journal of Clinical Neurology
2017;30(4):278-280
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compared the characteristics of cerebrovascular pathological changes in cerebral infarction patients accompanied with hyperhomocysteinemia (HHcy) and primary hypertension.Methods The level of homocysteine (Hcy) of 258 cerebral infarction patients with primary hypertension were detected, and patients were divided into H type hypertension group and hypertension group according to the level of Hcy.The cerebrovascular pathological changes were observed by DSA.Results There were 112 cases in H type hypertension group, and 146 cases in hypertension group.There had no significant difference between the two groups in gender, age, systolic pressure, diastolic pressure, and the rates of drinking and smoking (all P>0.05).Internal carotid artery (ICA) and middle cerebral artery (MCA) were involvements, and it was mainly with intracranial artery stenosis in the two groups.Compared with hypertension group, the rates of intracranial vessel lesion and severe cerebrovascular stenosis in H type hypertension group were significantly increased, and the rate of collateral vessels was significantly decreased(all P<0.05).Conclusion The stenosis of cerebrovascular seems much more narrower, heavier, and have less collateral circulation in cerebral infarction patients with H type hypertension.
