The influence of parenteral nutrition support to perioperative nutritional status and immune function in patients with neoadjuvant chemotherapy for gastric cancer
10.16151/j.1007-810x.2017.04.005
- VernacularTitle:肠外营养支持对胃癌新辅助化疗病人围术期营养状态和免疫功能的影响
- Author:
Jun ZHANG
;
Yue WANG
;
Yan ZHAO
;
Zhichao ZHENG
- Keywords:
Parenteral nutrition;
Gastric cancer;
Neoadjuvant chemotherapy Immune function
- From:
Parenteral & Enteral Nutrition
2017;24(4):209-212
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the influence of parenteral nutrition support on nutritional status and immune function in patients with neoadjuvant chemotherapy for gastric cancer.Methods:60 patients with locally advanced gastric cancer were randomly divided into PN group and control group,30 cases in each group.The nutritional status and immune function were compared.Results:Adverse reaction of chemotherapy in PN group was less than in control group (P < 0.05).ALB,TF.PA and IgA,IgG,IgM,CD4+ and CD4+/CD8+ were all higher in PN group than in control group 7 days after surgery (P < 0.05).Conclusion:Parenteral nutrition support is helpful to improve patients' nutritional state during chemotherapy and operation.