The clinical effect of enteral nutritional support combined with chemotherapy in advanced gastric cancer patients
10.16151/j.1007-810x.2017.04.004
- VernacularTitle:肠内营养联合化疗治疗晚期胃癌的临床疗效研究
- Author:
Mingquan CAI
;
Weiwei TANG
;
Hanxiang AN
;
Xiaohong LI
- Keywords:
Advanced gastric cancer;
Enteral nutrition;
Chemotherapy;
Nutritional Risk Screening 2002
- From:
Parenteral & Enteral Nutrition
2017;24(4):205-208
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of enteral nutrition support in inoperable advanced gastric cancer patients during chemotherapy.Methods:This was a prospective randomized study.A total of 62 patients with advanced gastric cancer were firsted evaluated according to the Nutritional Risk Screening 2002 (NRS 2002) scale,and were randomly divided into two groups.All patients received oxaliplatin combined with tegefur gimeracil oteraci.Patients in the control group (n =30) received chemotherapy along with nutrition consultation,and patients in the treatment group (n =32) were provided enteral nutrition-additionally.NRS 2002 assessment was conducted before and after chemotherapy,The body weight,BMI,serum albumin,and the efficacy and toxicity were collected during the study.Results:Patients in the treatment group had significantly higher serum albumin levels,body weight and BMI than those of the control group (P < 0.05).No differences were found as for the efficacy and toxicity of chemotherapy between two groups.Conclusion:Enteral nutrition support therapy can improve the nutrition status of gastric cancer patients who received chemotherapy and reduce the risk of malnutrition.