Clinical characteristics and risk factors of young patients with coronary heart disease complicated metabolic syndrome
10.3969/j.issn.1008-0074.2017.04.06
- VernacularTitle:青年冠心病伴代谢综合征患者的临床特点和危险因素
- Author:
Huanlun LI
;
Yuanchun ZHANG
;
Zhentuo GU
;
Lihua LU
;
Tong LIAO
- Keywords:
Coronary disease;
Metabolic syndrome X;
Risk factors
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2017;26(4):375-378
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study clinical characteristics and risk factors of young patients with coronary heart disease (CHD) complicated metabolic syndrome (MS).Methods: A total of 200 CHD young patients were selected from our hospital, including 100 patients with MS (CHD+MS group) and 100 patients without MS (CHD control group).Lesion severity was evaluated according to coronary lesion score.General data were compared between two groups,and risk factors were assessed CHD+MS group.Results: Compared with CHD control group, there were significant rise in body mass index (BMI), levels of total cholesterol (TC), 2h postprandial blood glucose (2hPG), fasting blood glucose (FBG), triglyceride (TG), blood pressure, serum uric acid (UA) and creatinine (Cr) and homeostasis model-insulin resistance index (HOMA-IR), and significant reduction in level of high density lipoprotein cholesterol (HDL-C) in CHD+MS group, P<0.01 all.Compared with CHD control group, there were significant rise in incidence rate of multi-vessel coronary disease (6% vs.32%) and Gensini score of coronary angiography [(5.1±2.0) scores vs.(8.4±5.3) scores] in CHD+MS group, P<0.01 both.Logistic regression analysis indicated that low HDL-C, HOMA-IR, hypertension and diabetes mellitus history were risk factors for CHD complicated MS in young patients(OR=1.097~2.246,P<0.01 all).Conclusion:There are much risk factors and abnormal metabolism,and coronary disease are more serious in young patients with CHD complicated MS.
