Correlation among serum vitamin D,folic acid and homocysteine levels in patients with type 2 diabetes mellitus
10.3969/j.issn.1008-0074.2017.04.07
- VernacularTitle:2型糖尿病患者血清中维生素D水平与叶酸、同型半胱氨酸的相关性
- Author:
Weici XIE
- Keywords:
Diabetes mellitus,type 2;
Vitamin D;
Folic acid;
Homocysteine
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2017;26(4):378-380
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore correlation among serum vitamin D, folic acid and homocysteine (Hcy) levels in patients with type 2 diabetes mellitus (T2DM).Methods: A total of 87 T2DM patients treated in our hospital were selected as DM group, another 90 healthy subjects undergoing physical examination were enrolled as healthy control group.Serum levels of vitamin D, folic acid and Hcy were measured and compared between two groups, and their correlation was analyzed.Results: Compared with healthy control group, there were significant reductions in levels of vitamin D [(32.85±5.31) ng/ml vs.(24.75±6.13) ng/ml] and folic acid [(13.31±2.10) nmol/ml vs.(8.47±2.59) nmol/ml], and significant rise in Hcy level [(14.36±4.28) μmol/ml vs.(22.43±5.32) μmol/ml] in DM group, P=0.001 all.Pearson correlation analysis indicated that in healthy control group and DM group, vitamin D level was significant positively correlated with folic acid level (r=0.617, 0.684, P<0.05 both) and significant inversely correlated with Hcy level (r=-0.554,-0.604, P<0.05 both), folic acid level was significant inversely correlated with Hcy level (r=-0.631,-0.779, P<0.01 both).Conclusion: Serum vitamin D level significant reduces, and is significantly correlated with levels of folic acid and homocysteine in patients with type 2 diabetes mellitus.Vitamin D level possesses important significance in monitoring cardiovascular and cerebrovascular complications in these patients.
